Trial reportThe Australian & New Zealand journal of obstetrics & gynaecology2011
Diet and IVF pilot study: short-term weight loss improves pregnancy rates in overweight/obese women undertaking IVF.
Trial report in The Australian & New Zealand journal of obstetrics & gynaecology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07242534 (Effect of Semaglutide on Embryo Quality in Overweight and Obese Patients Undergoing In Vitro Fertilization. A Randomized Controlled Trial), which is not on this map. Cited by 45 papers, 10 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effect of Semaglutide on Embryo Quality in Overweight and Obese Patients Undergoing In Vitro Fertilization. A Randomized Controlled Trial
Who cites it
45 citing papers in PubMed, 10 syntheses or guidelines pooled it, 107 citations in OpenAlex.
- Preconception lifestyle interventions for women-a systematic review and meta-analysis of intervention characteristics and behaviour change techniques.Human reproduction update · 2026Pooled it
- Effectiveness of preconception weight loss interventions on fertility in women: a systematic review and meta-analysis.Fertility and sterility · 2024Pooled it
- Comparative efficacy of exercise, diet and/or pharmacological interventions on BMI, ovulation, and hormonal profile in reproductive-aged women with overweight or obesity: a systematic review and network meta-analysis.Human reproduction update · 2024Pooled it
- Effect of weight loss before in vitro fertilization in women with obesity or overweight and infertility: a systematic review and meta-analysis.Scientific reports · 2024Pooled it
- The role of maternal physical activity on in vitro fertilization outcomes: a systematic review and meta-analysis.Archives of gynecology and obstetrics · 2023Pooled it
- The influence of lifestyle interventions and overweight on infertility: a systematic review, meta-analysis, and meta-regression of randomized controlled trials.Frontiers in medicine · 2023Pooled it
- Female dietary patterns and outcomes of in vitro fertilization (IVF): a systematic literature review.Nutrition journal · 2022Pooled it
- Preconception lifestyle advice for people with infertility.The Cochrane database of systematic reviews · 2021Pooled it
- Effectiveness of Non-Pharmacological Interventions for Overweight or Obese Infertile Women: A Systematic Review and Meta-Analysis.International journal of environmental research and public health · 2020Pooled it
- Maternal physical activity before IVF/ICSI cycles improves clinical pregnancy rate and live birth rate: a systematic review and meta-analysis.Reproductive biology and endocrinology : RB&E · 2018Pooled it
- Association between markers of female adiposity and live birth among patients undergoing fertility treatment or attempting unassisted conception.Human reproduction (Oxford, England) · 2025Trial
- Acceptability and feasibility of a planned preconception weight loss intervention in women with long-acting reversible contraception: the Plan-it mixed-methods study.Health technology assessment (Winchester, England) · 2023Trial
- A Pilot Randomized Controlled Trial of a Partial Meal Replacement Preconception Weight Loss Program for Women with Overweight and Obesity.Nutrients · 2021Trial
- Trial
- Trial
- Body mass index and short-term weight change in relation to treatment outcomes in women undergoing assisted reproduction.Fertility and sterility · 2012Trial
- Weight management in women of reproductive age.Obesity and endocrinology · 2026Review
- Impact of Physical Activity on Ovarian Response: A Prospective Study Among In Vitro Fertilization Patients.Cureus · 2025Article
- A multidisciplinary approach to weight management and reproductive care: a retrospective cohort study on weight loss through personalized and patient-centered care.Reproductive biology and endocrinology : RB&E · 2025Article
- Waist circumference mediates the relationship between atherogenic index of plasma and infertility.Frontiers in endocrinology · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Obesity worsens and modest weight loss improves female fertility. Overweight women were randomised to lifestyle or standard treatment pre-in vitro fertilisation with treatment cessation at embryo transfer. There was a greater reduction in weight (P < 0.001) for lifestyle treatment (-3.8 ± 3.0 kg, P < 0.001) compared with no changes for standard treatment (-0.5 ± 1.2 kg, P = 0.092). Both the intervention (-5.3 ± 4.6 cm) and control (-3.5 ± 3.5 cm) group had reductions in waist circumference (P < 0.001) with no differences between the two groups (P = 0.215). The overall pregnancy rate was 53% (20/38) for the intervention and control group combined.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.