DPP-4 inhibitors × glycemic control

TrialThe Journal of clinical endocrinology and metabolism2015

Effect of vildagliptin on hepatic steatosis.

Mavin Macauley et al.PubMed ↗Full text ↗Publisher ↗

What the trial testedas reported · 44 people · 2015

No range given

Reported lower glycemic control, no range given

−1.00mmol/L

As reported

difference −1.0 mmol/L, no interval

No range given

Reported higher glycemic control, no range given

+0.10percentage points

As reported

difference 0.1 %, no interval

No range given

Reported lower lipids, no range given

−0.10mmol/L

As reported

difference −0.10 mmol/L, no interval

No range given

Reported higher glycemic control, no range given

+0.30mmol/L

As reported

difference 0.3 mmol/L, no interval

+1 more in the walkthrough ↓

Five numbers in the abstract

the abstract, start to end

period with vildagliptin vs placebo by -1.0 mmol/L (P = .018), and there

Mean HbA1c changed by -0.5 ± 0.1% (P < .0001) from a baseline of

fasting triglyceride decreased by 0.2 ± 0.1 mmol/L from a baseline of 1.5 ±

fasting plasma glucose changed by -0.9 ± 0.3 mmol/L (P = .001) in the

1.6 ± 0.5 kg from a baseline of 82.6 ± 3.4 kg (P = .002) in the

← favours treatmentfavours comparator →
could be chance
No interval given · direction only, strength unknown
Glycemic control
−1.0
Glycemic control
0.1
Lipids
−0.10
Glycemic control
0.3
Body weight & composition
−3.40
DPP-4 inhibitorsGlycemic controlBody weight & compositionLipids

DPP-4 inhibitors × glycemic controlhelps?replicated

unlikelylikely
0.820.84 without it

DPP-4 inhibitors × body weight & compositionhelps?mixed

unlikelylikely
0.500.43 without it
← favours treatmentfavours comparator →
this papermore certainless certain
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