← Statins × glycemic control

Observational studyJournal of general internal medicine2016

Statin Use, Diabetes Incidence and Overall Mortality in Normoglycemic and Impaired Fasting Glucose Patients.

M Regina Castro et al.PubMed ↗Full text ↗Publisher ↗

What the trial testedas reported · 6,325 people · 2016

Not counted

Reduced deaths

−30%−34% to −20%

Bigger than 8 in 10 for all-cause mortality

As reported

HR 0.70, 95% CI 0.66–0.80 · the paper's word: All-cause mortality

Not counted

Reduced deaths

−23%−36% to −9%

Bigger than 7 in 10 for all-cause mortality

As reported

HR 0.77, 95% CI 0.64–0.91 · the paper's word: All-cause mortality

What moved togetherboth groups pooled, not the treatment’s effect

Correlation, not cause

Went with higher glycemic control

+19%+5% to +35%

Bigger than 1 in 10 for glycemic control

As reported

HR 1.19, 95% CI 1.05–1.35

Correlation, not cause

Went with higher glycemic control

+24%+11% to +38%

Bigger than 2 in 10 for glycemic control

As reported

HR 1.24, 95% CI 1.11–1.38

Four numbers in the abstract

the abstract, start to end

… diabetes in the normoglycemic (HR 1.19; 95% CI, 1.05 to 1.35; p = 0.007) and IFG groups (HR 1.24; 95%CI, 1.11 to 1.38; …

… decreased in both normoglycemic (HR 0.70; 95% CI, 0.66 to 0.80; p < 0.0001) and IFG patients (HR 0.77, 95% CI, 0.64 to 0.91; …

← favours treatmentfavours comparator →
could be chance
Glycemic control
HR 1.191.05–1.35
Glycemic control
HR 1.241.11–1.38
All-cause mortality
HR 0.700.66–0.80
All-cause mortality
HR 0.770.64–0.91
StatinsGlycemic controlAll-cause mortality
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2016
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this papercites it
Full record →Abstract, authors, funding and every citing paper · PMID 26850412