SynthesisOncotarget2016

Metformin therapy associated with survival benefit in lung cancer patients with diabetes.

What moved togetherboth groups pooled, not the treatment’s effect

Correlation, not cause

−35%−48% to −17%

Bigger than 8 in 10 for all-cause mortality

As reported

HR 0.65, 95% CI 0.52–0.83 · the paper's word: All-cause mortality

Correlation, not cause

−22%−36% to −7%

Bigger than 7 in 10 for all-cause mortality

As reported

HR 0.78, 95% CI 0.64–0.93 · the paper's word: All-cause mortality

the abstract, start to end

… patients with diabetes(for DFS: HR = 0.65, 95%CI = 0.52-0.83; for OS: HR = 0.78, 95%CI = 0.64-0.93).

← favours treatmentfavours comparator →

could be chance

All-cause mortality

HR 0.650.52–0.83

All-cause mortality

HR 0.780.64–0.93

MetforminAll-cause mortality

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this paperpooled ittrialcites it