Statins × blood pressure

TrialJAMA cardiology2016

Association of Lipoproteins, Insulin Resistance, and Rosuvastatin With Incident Type 2 Diabetes Mellitus : Secondary Analysis of a Randomized Clinical Trial.

Sagar B Dugani et al.PubMed ↗Full text ↗Publisher ↗

What the trial testedrandomised · 9,180 people · 2016

Randomised comparison

Raised blood pressure

+35%+3% to +76%

Bigger than 6 in 10 on the map

As reported

HR 1.35, 95% CI 1.03–1.76

Randomised comparison

Raised blood pressure

1.6×1.3× to 2×

Bigger than 7 in 10 on the map

As reported

HR 1.60, 95% CI 1.27–2.03

Two numbers in the abstract

the abstract, start to end

with T2DM in the placebo arm (HR, 1.35; 95% CI, 1.03-1.76) and rosuvastatin arm (HR, 1.60; 95% CI, 1.27-2.03).

← favours treatmentfavours comparator →
could be chance
Blood pressure
HR 1.351.03–1.76
Blood pressure
HR 1.601.27–2.03
StatinsBlood pressure

Statins × blood pressurehelps?replicated

unlikelylikely
0.830.80 without it
← favours comparatorfavours treatment →
this papermore certainless certain
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The trial

Full record →Abstract, authors, funding and every citing paper · PMID 27347563