Who was studied, and how
Three numbers in the abstract
Where each one falls
Only readable comparisons vote
Where it lands on the map
What it changes
Among 23 other studies
people with hypertension, in this paper
The trial randomly assignedassigned by chance
Exenatide-infusion
placebo
Reported higher RHR, no range given+7.50
randomisedThe trial randomly assignedassigned by chance
liraglutide
placebo
Reported higher RHR, no range given+6.60
Reported lower systolic BP, no range given−12.6
randomisedthe abstract, start to end
… increased RHR (mean ± s.e.m. +7.5 ± 0.9 BPM, P < 0.001), and …
… with liraglutide increased RHR (+6.6 ± 2.1 BPM), while reducing systolic BP (-12.6 ± 4.7 mmHg) and stroke volume …
← favours treatmentfavours comparator →
could be chanceNo interval given · direction only, strength unknown
RHRExenatide-infusion vs placebo
7.5
RHRliraglutide vs placebo
6.6
Systolic BPliraglutide vs placebo
−12.6
GLP-1 receptor agonistsBody weight & compositionBlood pressureCardiac & vascular function
GLP-1 receptor agonists × body weight & compositionhelps?replicated
unlikelylikely
0.900.91 without it
GLP-1 receptor agonists × blood pressurehelps?mixed
unlikelylikely
0.500.39 without it
← favours treatmentfavours comparator →
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