ArticlePloS one2017
Obesity and access to kidney transplantation in patients starting dialysis: A prospective cohort study.
Article in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04529278 (Efficacy and Tolerance of Liraglutide for Weight Loss in Obese Type 2 Diabetic Hemodialysis Patients), which is not on this map. Cited by 22 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Efficacy and Tolerance of Liraglutide for Weight Loss in Obese Type 2 Diabetic Hemodialysis Patients
Who cites it
22 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Effects of Weight-Loss Interventions on Kidney, Cardiometabolic and Anthropometric Outcomes in Adults With CKD and Overweight or Obesity: A Systematic Review and Meta-Analysis.Diabetes, obesity & metabolism · 2026Pooled it
- Interventions for weight loss in people with chronic kidney disease who are overweight or obese.The Cochrane database of systematic reviews · 2021Pooled it
- Bariatric Surgery as a Bridge to Kidney Transplantation in Patients with Obesity and Advanced Chronic Kidney Disease or End-Stage Renal Disease: A Systematic Review.Obesity surgery · 2026Review
- Outcomes After Bariatric Surgery in Older Adults With Obesity and End-Stage Kidney Disease.World journal of surgery · 2025Article
- Impact of Race on Outcomes in Obese Kidney Transplant Recipients: A Mate Kidney Analysis.Journal of racial and ethnic health disparities · 2025Article
- GLP-1 Receptor Agonist Outcomes, Safety, and Body Mass Index Change in a National Cohort of Patients on Dialysis.Clinical journal of the American Society of Nephrology : CJASN · 2025Article
- Approaches to patients with obesity and CKD: focus on nutrition and surgery.Clinical kidney journal · 2024Article
- Evaluating the safety of bariatric surgery as a bridge to kidney transplant: a retrospective cohort study.Surgical endoscopy · 2024Article
- Prevalence, Characteristics, and Outcomes of People With A High Body Mass Index Across the Kidney Disease Spectrum: A Population-Based Cohort Study.Canadian journal of kidney health and disease · 2024Article
- Should Bariatric Surgery Play a Larger Role in the Management of Pediatric Patients with Severe Obesity and End-Stage Organ Disease?Obesity surgery · 2023Article
- Associations of body mass index (BMI) and BMI change with progression of chronic kidney disease in children.Pediatric nephrology (Berlin, Germany) · 2023Article
- The role of bariatric surgery on kidney transplantation: A systematic review and meta-analysis.Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2021Review
- Renal transplantation outcomes in obese patients: a French cohort-based study.BMC nephrology · 2021Article
- Clinical outcome of kidney transplantation after bariatric surgery: A single-center, retrospective cohort study.Clinical transplantation · 2021Article
- Effects of body weight variation in obese kidney recipients: a retrospective cohort study.Clinical kidney journal · 2020Article
- Metabolic syndrome in haemodialysis patients: prevalence, determinants and association to cardiovascular outcomes.BMC nephrology · 2020Observational
- Article
- Weighing the waitlist: Weight changes and access to kidney transplantation among obese candidates.PloS one · 2020Article
- The obesity paradox: A further consideration in dialysis patients.Seminars in dialysis · 2019Article
- Bariatric surgery before and after kidney transplantation: long-term weight loss and allograft outcomes.Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundObesity has been linked to poor access to medical care. Although scientific evidence suggest that kidney transplantation improves survival and quality of life in obese patients with end-stage renal disease (ESRD), few data exist on the impact of obesity on access to kidney transplantation in this population.
objectivesWe aimed to characterize the relationships between body mass index (BMI) at the start of dialysis, changes in BMI after the start of dialysis, and either access to kidney transplantation or overall mortality in dialysis or transplantation among ESRD patients.
methodsBetween 2002 and 2011, 19524 dialysis patients with ESRD were included in the study via the French nationwide Renal Epidemiology and Information Network. Data on sociodemographic factors, comorbidities and laboratory test results were recorded upon entry into the registry. BMI were obtained at the start of dialysis and then yearly. Cubic spline regression analyses provided a graphic evaluation of the relationships between BMI at the start of dialysis and outcomes. Joint models were used to evaluate the association between the change over time in BMI and outcomes.
resultsDuring a median follow-up of 20.3 months, 6634 patients underwent kidney transplantation. A BMI >31 kg/m2 at the start of the dialysis was associated with a lower likelihood of receiving a kidney transplant, and the likelihood decreased even further with higher BMI values. For patients with BMI ≥30kg/m2 at the start of the dialysis, a 1 kg/m2 decrease in BMI during follow-up was associated with a 9% to 11% increase in the likelihood of receiving a transplant. There was an L-shaped relationship between BMI at the start of dialysis and overall mortality. We showed that obese patients with ESRD face barriers to the receipt of a kidney transplant without valid reasons.
conclusionGreater attention to this issue would improve the fairness of the organ allocation process and might improve outcomes for obese patients with ESRD.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.