Evidence map›Paper›PMID 29221938›Full record

ArticleObesity research & clinical practice

Are women with obesity and infertility willing to attempt weight loss prior to fertility treatment?

C R Sacha, C M Page, R H Goldman, E S Ginsburg, C A Zera

Registry-linked trialAbstract readLetter
PubMed Publisher
In one paragraph

Article in Obesity research & clinical practice. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It reports registered trial NCT07242534. Cited by 7 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07242534 phase4recruiting

Effect of Semaglutide on Embryo Quality in Overweight and Obese Patients Undergoing In Vitro Fertilization. A Randomized Controlled Trial

Ran2026Enrolled62Registered outcomes23Posted comparisons0ConditionsInfertility, ObesityArmsNo pre-treatment, semaglutide
PMID 29703793PMID 33567185PMID 36551163PMID 21806596PMID 26097395PMID 29523133PMID 30763543PMID 30910544PMID 31260047PMID 33257906PMID 36635080PMID 37427372other papers from this trial
Open the trial in the graph
3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Review
  5. Review
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

C R SachaDept. of Obstetrics & Gynecology, Center for Infertility and Reproductive Surgery, Brigham & Women's Hospital and Harvard Medical School, 75 Francis Street, Boston, MA 02115, United States. Electronic address: csacha@partners.org.
C M PageDept. of Obstetrics & Gynecology, Center for Infertility and Reproductive Surgery, Brigham & Women's Hospital and Harvard Medical School, 75 Francis Street, Boston, MA 02115, United States. Electronic address: charlotte.page@duke.edu.
R H GoldmanDept. of Obstetrics & Gynecology, Center for Infertility and Reproductive Surgery, Brigham & Women's Hospital and Harvard Medical School, 75 Francis Street, Boston, MA 02115, United States. Electronic address: rhgoldman@bwh.harvard.edu.
E S GinsburgDept. of Obstetrics & Gynecology, Center for Infertility and Reproductive Surgery, Brigham & Women's Hospital and Harvard Medical School, 75 Francis Street, Boston, MA 02115, United States. Electronic address: eginsburg@bwh.harvard.edu.
C A ZeraDept. of Obstetrics and Gynecology, Division of Maternal Fetal Medicine, Brigham and Women's Hospital and Harvard Medical School, 75 Francis Street, Boston, MA 02115, United States. Electronic address: czera@bwh.harvard.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo assess attitudes towards weight loss interventions in patients seeking infertility treatment.

methodsWe evaluated prior weight loss experiences, attitudes towards future interventions by body mass index (BMI), and willingness to delay fertility treatment for weight loss interventions stratified by BMI using logistic regression amongst women ≤45years old with infertility over three months or recurrent pregnancy loss.

resultsThe average age of our convenience sample of respondents (148 of 794 eligible women, 19%) was 34.5 years old, with a mean BMI of 26.7±7.4kg/m

conclusionMost women with obesity and infertility in our population are unwilling to postpone fertility treatment for weight loss interventions.

Indexed as

Preconception CareReproductive Techniques, AssistedAdultBody Mass IndexFemaleHumansInfertilityObesityPatient ComplianceTime-to-PregnancyWeight LossWeight Reduction ProgramsYoung AdultInfertilityObesityWeight loss

Identifiers

PMID29221938

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.