GLP-1 receptor agonists × blood pressure

SynthesisBMC endocrine disorders2019

Effect of liraglutide on blood pressure: a meta-analysis of liraglutide randomized controlled trials.

Xu Zhao et al.PubMed ↗Full text ↗Publisher ↗

What the trial testedrandomised · 7,616 people · 2019

Randomised comparison

Raised blood pressure

+0.47mmHg+0.11 to +0.83

As reported

difference 0.47 mmHg, 95% CI 0.11–0.83

Range includes no effect

No clear effect on blood pressure

−1.46mmHg−2.61 to +0.32

As reported

difference −1.46 mmHg, 95% CI −2.61 to 0.32

Two numbers in the abstract

the abstract, start to end

3.0 mg/d significantly reduced DBP by 1.46 mmHg (95% CI -2.61, 0.32), P = 0.01, but liraglutide 1.8 mg/d slightly increased DBP by 0.47 mmHg (95% CI 0.11, 0.83),

← favours treatmentfavours comparator →
could be chance
Blood pressure
−1.46−2.61 to 0.32
Blood pressure
0.470.11–0.83
GLP-1 receptor agonistsBlood pressure

GLP-1 receptor agonists × blood pressurehelps?mixed

unlikelylikely
0.50not counted
← favours treatmentfavours comparator →
more certainless certain
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Full record →Abstract, authors, funding and every citing paper · PMID 30616638