Evidence mapPaperPMID 30763543Full record

ArticleAmerican journal of obstetrics and gynecology2019

Waist circumference in relation to outcomes of infertility treatment with assisted reproductive technologies.

Ming-Chieh Li, Lidia Mínguez-Alarcón, Mariel Arvizu, Yu-Han Chiu, Jennifer B Ford, Paige L Williams, Jill Attaman, Russ Hauser, Jorge E Chavarro, EARTH Study Team

Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in American journal of obstetrics and gynecology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07242534 (Effect of Semaglutide on Embryo Quality in Overweight and Obese Patients Undergoing In Vitro Fertilization. A Randomized Controlled Trial), which is not on this map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07242534 phase4recruitingstarted 2026, after this paper: background citation

Effect of Semaglutide on Embryo Quality in Overweight and Obese Patients Undergoing In Vitro Fertilization. A Randomized Controlled Trial

Ran2026Enrolled62Registered outcomes23Posted comparisons0ConditionsInfertility, ObesityArmsNo pre-treatment, semaglutide
Open the trial in the graph
3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 30 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. [Analysis of Risk Factors for Recurrent Pregnancy Loss in Patients UndergoingSichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2024
    Article
  13. Article
  14. Article
  15. Article
  16. Observational
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Ming-Chieh LiDepartment of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA; Department of Public Health, China Medical University College of Public Health, Taichung, Taiwan.
Lidia Mínguez-AlarcónDepartment of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, MA.
Mariel ArvizuDepartment of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA.
Yu-Han ChiuDepartment of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA.
Jennifer B FordDepartment of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, MA.
Paige L WilliamsDepartment of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA.
Jill AttamanDepartment of Obstetrics and Gynecology, Division of Reproductive Endocrinology and Infertility, Massachusetts General Hospital Fertility Center Harvard Medical School, Boston, MA.
Russ HauserDepartment of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, MA.
Jorge E ChavarroDepartment of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA; Channing Division of Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA. Electronic address: jchavarr@hsph.harvard.edu.
EARTH Study Team
Harvard University · USBrigham and Women's Hospital · US

Funding

TOXICOLOGYP30ES000002 · NIEHS · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI Marc G Weisskopf · 1985 to 2023
$12.4M
SIGNAL TRANSDUCTION IN HUMAN ABDOMINAL AND GLUTEOFEMORAL ADIPOCYTESP30DK046200 · TUFTS MEDICAL CENTER · 1992 to 2005
$5.3M
PCBs, Phthalates and Male Reproductive HealthR01ES009718 · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · 1999 to 2005
$2.9M
NIDDK NIH HHS P30 DK046200NIEHS NIH HHS P30 ES000002NIEHS NIH HHS R01 ES009718NIEHS NIH HHS R01 ES022955
6 · The paper itself

Abstract

backgroundMany studies have documented a lower likelihood of live birth with increasing body mass index among women undergoing assisted reproductive technology, but few have examined the association with waist circumference, an anthropometric measure that allows assessment of central adiposity.

objectiveTo examine the relation between baseline waist circumference and infertility treatment outcomes among women undergoing treatment with assisted reproductive technology. MATERIALS AND

methodsWe followed up 264 women who underwent 445 assisted reproductive technology cycles for infertility treatment at the Massachusetts General Hospital between 2010 and 2017. Waist circumference was assessed at enrollment. We used cluster-weighted generalized estimating equation models to estimate the probability of live birth by tertiles of waist circumference (<77, 77-86, >86 cm), while accounting for multiple treatment cycles per woman and adjusting for age, race, smoking, infertility diagnosis, day 3 follicle-stimulating hormone, body mass index, and height.

resultsMean (standard deviation) waist circumference and body mass index were 83.6 (12.6) cm and 24.1 (4.3) kg/m

conclusionWaist circumference was inversely related to the probability of live birth among women undergoing assisted reproductive technology independently of body mass index.

Indexed as

Reproductive Techniques, AssistedWaist CircumferenceAdultFemaleFertilization in VitroHumansInfertilityLive BirthObesity, AbdominalPregnancyPregnancy in ObesitySperm Injections, Intracytoplasmicassisted reproductive technologybody mass indexICSIintracytoplasmic sperm injectionin vitro fertilizationIVFwaist circumference

Identifiers

PMID30763543
PMCPMC6545132
OpenAlexW2913138949

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.