← Metformin × all-cause mortality

SynthesisCritical care (London, England)2019

Association of preadmission metformin use and mortality in patients with sepsis and diabetes mellitus: a systematic review and meta-analysis of cohort studies.

Huoyan Liang et al.PubMed ↗Full text ↗Publisher ↗

What the trial testedas reported · 1,282 people · 2019

Not counted

Lowered costs & health-care use

−41%−57% to −21%

Bigger than 8 in 10 on the map

As reported

OR 0.59, 95% CI 0.43–0.79

Not counted

Lowered costs & health-care use

−41%−57% to −21%

Bigger than 8 in 10 on the map

As reported

OR 0.59, 95% CI 0.43–0.79

What moved togetherboth groups pooled, not the treatment’s effect

Correlation, not cause

Went with fewer deaths

−41%−57% to −21%

Bigger than 9 in 10 for all-cause mortality

As reported

OR 0.59, 95% CI 0.43–0.79 · the paper's word: All-cause mortality

Three numbers in the abstract

the abstract, start to end

… significantly lower mortality rate (OR, 0.59; 95% CI, 0.43-0.79, P = 0.001).

… nonusers among patients with sepsis (OR, 0.59; 95% CI, 0.43-0.79, P …

… nonusers among patients with sepsis (OR, 0.59; 95% CI, 0.43-0.79, P …

← favours treatmentfavours comparator →
could be chance
All-cause mortality
OR 0.590.43–0.79
Costs & health-care use
OR 0.590.43–0.79
Costs & health-care use
OR 0.590.43–0.79
MetforminAll-cause mortalityCosts & health-care use
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Full record →Abstract, authors, funding and every citing paper · PMID 30777119