Observational studyCardiovascular diabetology2019
Weight change and mortality and cardiovascular outcomes in patients with new-onset diabetes mellitus: a nationwide cohort study.
Observational study in Cardiovascular diabetology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 3 of them syntheses that pooled it.
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Who cites it
35 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Association of magnitude of weight loss and weight variability with mortality and major cardiovascular events among individuals with type 2 diabetes mellitus: a systematic review and meta-analysis.Cardiovascular diabetology · 2022Pooled it
- Pooled it
- Glucagon-like Peptide-1 Receptor Agonists and Cardioprotective Benefit in Patients with Type 2 Diabetes Without Baseline Metformin: A Systematic Review and Update Meta-analysis.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2021 · on this mapPooled it
- Body weight time in target range and cardiovascular outcomes in adults with overweight/obesity and type 2 diabetes.European journal of preventive cardiology · 2023Trial
- Article
- Long-term metabolic risks after thyroidectomy and thyroid hormone therapy in thyroid cancer survivors: a nationwide cohort study.Frontiers in endocrinology · 2026Article
- Differences in cardiovascular disease incidence according to changes in obesity status in young diabetic patients.Cardiovascular diabetology. Endocrinology reports · 2025Article
- Weight change and diabetes risk following breast cancer: a nationwide cohort study.Journal of cancer survivorship : research and practice · 2025Article
- Association between weight changes and infective endocarditis in patients with diabetes: A nationwide population-based cohort study.International journal of obesity (2005) · 2025Article
- Association of childhood-adulthood body size trajectories with risk of micro- and macrovascular complications among individuals with type 2 diabetes: a prospective study.Diabetology & metabolic syndrome · 2024Article
- Weight change and the risk of cardiovascular disease in patients with hypertension: A primary-care cohort study.Journal of global health · 2024Article
- Weight Change and the Risk of Micro and Macro Vascular Complications of Diabetes: A Systematic Review.The Malaysian journal of medical sciences : MJMS · 2024Review
- Racial and ethnic disparities in the association between financial hardship and self-reported weight change during the first year of the pandemic in the U.S.International journal for equity in health · 2024Article
- Trajectories of Body Mass Index and Risk for Diabetes Complications and All-Cause Mortality in Finnish Type 2 Diabetes Patients.Clinical epidemiology · 2024Article
- Factors Affecting High Body Weight Variability.Journal of obesity & metabolic syndrome · 2023Article
- Effects of Weight Loss and Interaction with Physical Activity on Risks of Cardiovascular Outcomes in Individuals with Type 2 Diabetes.Endocrinology and metabolism (Seoul, Korea) · 2023Article
- Weight Change Since Age 20 and the Risk of Cardiovascular Disease Mortality: A Prospective Cohort Study.Journal of atherosclerosis and thrombosis · 2022Article
- The associations of hepatic steatosis and fibrosis using fatty liver index and BARD score with cardiovascular outcomes and mortality in patients with new-onset type 2 diabetes: a nationwide cohort study.Cardiovascular diabetology · 2022Article
- Weight Change, Lifestyle, and Mortality in Patients With Type 2 Diabetes.The Journal of clinical endocrinology and metabolism · 2022Observational
- Weight Changes in Type 2 Diabetes and Cancer Risk: A Latent Class Trajectory Model Study.Obesity facts · 2022Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundBecause weight control is a cornerstone of diabetes management, it is important to understand the relationship of weight change to risk of cardiovascular disease (CVD) among patients with type 2 diabetes mellitus (DM). We aimed to investigate whether changes in weight early after diagnosis influence the incidence of CVD and all-cause mortality in patients with type 2 DM.
methodsUsing nationally representative data from the Korean National Health Insurance System, 173,246 subjects with new-onset DM who underwent health examinations during 2007-2012 were included. Weight was measured at the time of diabetes diagnosis and 2 years later. Weight change over 2 years was divided into five categories of 5% weight change, from weight loss ≥ - 10% to weight gain ≥ 10%.
resultsThere were 3113 deaths (1.8%), 2060 cases of stroke (1.2%), and 1767 myocardial infarctions (MIs) (1.0%) during a median follow-up of 5.5 years. Subjects with weight gain ≥ 10% had a significantly higher risk of stroke (hazard ratio [HR] 1.51, 95% confidence interval [CI] 1.23-1.84), compared with the group with stable weight. There was no significant association between weight change after diagnosis of DM and incident MI. All-cause mortality showed a U-shaped curve according to weight change. The group with weight loss ≥ - 10% had the highest HR for all-cause mortality (HR 1.86; 95% CI 1.61-2.14) and the HR for weight gain ≥ 10% was 1.61 (95% CI 1.37-1.89).
conclusionsWeight changes of more than 10% after diabetes diagnosis were associated with higher mortality and over 10% weight gain was associated with increased risk of stroke.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.