Evidence map›Paper›PMID 31597293›Full record

ArticleNutrients2019

Human Milk Oligosaccharide, Phospholipid, and Ganglioside Concentrations in Breast Milk from United Arab Emirates Mothers: Results from the MISC Cohort.

Paul McJarrow, Hadia Radwan, Lin Ma, Alastair K H MacGibbon, Mona Hashim, Hayder Hasan, Reyad Shaker Obaid, Farah Naja, Hamid Jan Jan Mohamed, Hessa Al Ghazal and 1 more

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 4 countries.

Paul McJarrowFonterra Research and Development Centre, Dairy Farm Road, Private Bag 11029, Palmerston North 4442, New Zealand. paul.mcjarrow@fonterra.com.ORCID 0000-0002-3367-0997
Hadia RadwanDepartment of Clinical Nutrition and Dietetics, College of Health Sciences, Research Institute of Medical and Health Sciences (RIMHS), University of Sharjah, Sharjah 27272, UAE. hradwan@sharjah.ac.ae.ORCID 0000-0002-3930-2554
Lin MaFonterra Research and Development Centre, Dairy Farm Road, Private Bag 11029, Palmerston North 4442, New Zealand. kevin.ma@fonterra.com.
Alastair K H MacGibbonFonterra Research and Development Centre, Dairy Farm Road, Private Bag 11029, Palmerston North 4442, New Zealand.
Mona HashimDepartment of Clinical Nutrition and Dietetics, College of Health Sciences, Research Institute of Medical and Health Sciences (RIMHS), University of Sharjah, Sharjah 27272, UAE. mhashim@sharjah.ac.ae.
Hayder HasanDepartment of Clinical Nutrition and Dietetics, College of Health Sciences, Research Institute of Medical and Health Sciences (RIMHS), University of Sharjah, Sharjah 27272, UAE. haidarah@sharjah.ac.ae.ORCID 0000-0001-5580-1911
Reyad Shaker ObaidDepartment of Clinical Nutrition and Dietetics, College of Health Sciences, Research Institute of Medical and Health Sciences (RIMHS), University of Sharjah, Sharjah 27272, UAE. robaid@sharjah.ac.ae.
Farah NajaDepartment of Nutrition and Food Sciences, American University of Beirut, Beirut 1107 2020, Lebanon. fn14@aub.edu.lb.
Hamid Jan Jan MohamedSchool of Health Sciences, Universiti Sains Malaysia, Kubang Kerian 16150, Malaysia. hamidjan@usm.my.
Hessa Al GhazalFamily Health Promotion Centre, Sharjah 27272, UAE. Hessa.ALGhazal@scf.shj.ae.
Bertram Y FongFonterra Research and Development Centre, Dairy Farm Road, Private Bag 11029, Palmerston North 4442, New Zealand. bertram.fong@fonterra.com.
Fonterra (New Zealand) · NZUniversity of Sharjah · AEUniversiti Sains Malaysia · MYAmerican University of Beirut · LB

Funding

Al Jalila Foundataion AJF 201510University of Sharjah Collaborative Grant 1501057003-P
6 · The paper itself

Abstract

Human milk oligosaccharides (HMOs), phospholipids (PLs), and gangliosides (GAs) are components of human breast milk that play important roles in the development of the rapidly growing infant. The differences in these components in human milk from the United Arab Emirates (UAE) were studied in a cross-sectional trial. High-performance liquid chromatography‒mass spectrometry was used to determine HMO, PL, and GA concentrations in transitional (5-15 days) and mature (at 6 months post-partum) breast milk of mothers of the United Arab Emirates (UAE). The results showed that the average HMO (12 species), PL (7 species), and GA (2 species) concentrations quantified in the UAE mothers' transitional milk samples were (in mg/L) 8204 ± 2389, 269 ± 89, and 21.18 ± 11.46, respectively, while in mature milk, the respective concentrations were (in mg/L) 3905 ± 1466, 220 ± 85, and 20.18 ± 9.75. The individual HMO concentrations measured in this study were all significantly higher in transitional milk than in mature milk, except for 3 fucosyllactose, which was higher in mature milk. In this study, secretor and non-secretor phenotype mothers showed no significant difference in the total HMO concentration. For the PL and GA components, changes in the individual PL and GA species distribution was observed between transitional milk and mature milk. However, the changes were within the ranges found in human milk from other regions.

Indexed as

Cohort StudiesCross-Sectional StudiesFemaleGangliosidesHumansInfantInfant, NewbornLactationMilk, HumanOligosaccharidesPhenotypePhospholipidsUnited Arab EmiratesGangliosidesOligosaccharidesPhospholipidsgangliosideshuman milkhuman milk oligosaccharidesLC–MSphospholipidssphingomyelin

Identifiers

PMID31597293
PMCPMC6835464
OpenAlexW2979961602

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.