Evidence mapPaperPMID 31926951Full record

Trial reportAmerican journal of obstetrics and gynecology2020

Early gestational diabetes screening in obese women: a randomized controlled trial.

Lorie M Harper, Victoria Jauk, Sherri Longo, Joseph R Biggio, Jeff M Szychowski, Alan T Tita

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in American journal of obstetrics and gynecology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06704035 (Early Screening for Gestational Diabetes Mellitus in a Low Risk Population), which is not on this map. Cited by 44 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed, 1 pooled it
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06704035 nanot yet recruitingnot on this mapstarted 2024, after this paper: background citation

Early Screening for Gestational Diabetes Mellitus in a Low Risk Population

TypeinterventionalSponsorNational University Hospital, SingaporeRan2024 to 2026Enrolled120ConditionsGestational Diabetes Mellitus (GDM), Glucose Intolerance During PregnancyArmsEarly OGTT Results Revealed
3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Trial
  4. Trial
  5. Postpartum glucose intolerance following early gestational diabetes mellitus.American journal of obstetrics & gynecology MFM · 2022
    Trial
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  11. Observational
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  15. Review
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  19. Time to Move Beyond a Binary Criterion for Gestational Diabetes?Reproductive sciences (Thousand Oaks, Calif.) · 2024
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Lorie M HarperDepartment of Obstetrics and Gynecology, Center for Women's Reproductive Health, University of Alabama at Birmingham, Birmingham, AL. Electronic address: lmharper@uabmc.edu.
Victoria JaukDepartment of Obstetrics and Gynecology, Center for Women's Reproductive Health, University of Alabama at Birmingham, Birmingham, AL.
Sherri LongoWomen's Services Center of Excellence, Ochsner Health System, New Orleans, LA.
Joseph R BiggioDepartment of Obstetrics and Gynecology, Center for Women's Reproductive Health, University of Alabama at Birmingham, Birmingham, AL; Women's Services Center of Excellence, Ochsner Health System, New Orleans, LA.
Jeff M SzychowskiDepartment of Obstetrics and Gynecology, Center for Women's Reproductive Health, University of Alabama at Birmingham, Birmingham, AL.
Alan T TitaDepartment of Obstetrics and Gynecology, Center for Women's Reproductive Health, University of Alabama at Birmingham, Birmingham, AL.

Funding

OB/GYN FACULTY RESEARCH CAREER DEVELOPMENT PROGRAMK12HD001258 · UNIVERSITY OF ALABAMA AT BIRMINGHAM · 1999 to 2005
$1.6M
UAB Diabetes Research CenterP30DK079626 · UNIVERSITY OF ALABAMA AT BIRMINGHAM · 2025 to 2025
$1.3M
NCATS NIH HHS UL1 TR001417NCATS NIH HHS UL1 TR003096NICHD NIH HHS K12 HD001258NIDDK NIH HHS P30 DK079626
6 · The paper itself

Abstract

backgroundAlthough in 2013 the American College of Obstetricians and Gynecologists recommended early screening for gestational diabetes in obese women, no studies demonstrate an improvement in perinatal outcomes with this strategy.

objectiveWe sought to determine whether early screening for gestational diabetes improves perinatal outcomes in obese women. MATERIALS AND

methodsRandomized controlled trial comparing early gestational diabetes screening (14-20 weeks) to routine screening (24-28 weeks) in obese women (body mass index ≥30 kg/m

resultsA total of 962 women were randomized, and outcomes were available for 922. Of these 922 women, 459 (49.8%) were assigned to early screen and 463 (50.2%) to routine screen. Baseline characteristics were balanced between groups. In the early screening group, 69 (15.0%; 95% confidence interval, 11.9-18.6%) were diagnosed with gestational diabetes: 29 (6.3%; 95% confidence interval, 4.3-8.9%) at <20 weeks and 40 (8.7%; 95% confidence interval, 6.3-11.7%) at >24 weeks. Of those randomized to routine screening, 56 (12.1%; 95% confidence interval, 9.3-15.4%) had gestational diabetes. Early screening did not reduce the incidence of the primary outcome (56.9% in the early screen versus 50.8% in the routine screen, P = .07; relative risk, 1.12; 95% confidence interval, 0.99-1.26).

conclusionEarly screening for gestational diabetes in obese women did not reduce the composite perinatal outcome.

Indexed as

AdultDiabetes, GestationalEarly DiagnosisFemaleHumansInfant, NewbornMass ScreeningObesityPregnancyPregnancy OutcomePregnancy Trimester, SecondYoung Adultcesarean deliveryearly screeninggestational diabetesmacrosomiaobesitypreeclampsiarandomized trialshoulder dystocia

Identifiers

PMID31926951
PMCPMC7196002

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.