← Statins × all-cause mortality

SynthesisDrugs & aging2020

Association between Statins Prescribed for Primary and Secondary Prevention and Major Adverse Cardiac Events among Older Adults with Frailty: A Systematic Review.

Matthew Hale et al.PubMed ↗Publisher ↗

What moved togetherboth groups pooled, not the treatment’s effect

Correlation, not cause

Went with fewer deaths

−42%−63% to −7%

Bigger than 9 in 10 for all-cause mortality

As reported

HR 0.58, 95% CI 0.37–0.93 · the paper's word: All-cause mortality

Correlation · may be no link

No clear link with deaths

−19%−39% to +8%

Bigger than 6 in 10 for all-cause mortality

As reported

HR 0.81, 95% CI 0.61–1.08 · the paper's word: All-cause mortality

Correlation, not cause

Went with fewer deaths

−72%−79% to −61%

Bigger than almost all for all-cause mortality

As reported

HR 0.28, 95% CI 0.21–0.39 · the paper's word: All-cause mortality

Three numbers in the abstract

the abstract, start to end

… reduced mortality (hazard ratio [HR] 0.58, 95% confidence interval [CI] 0.37-0.93), while another study found they were not (HR 0.81, 95% CI 0.61-1.08).

… associated with reduced mortality (HR 0.28, 95% CI 0.21-0.39).

← favours treatmentfavours comparator →
could be chance
All-cause mortality
HR 0.580.37–0.93
All-cause mortality
HR 0.810.61–1.08
All-cause mortality
HR 0.280.21–0.39
StatinsAll-cause mortality
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Full record →Abstract, authors, funding and every citing paper · PMID 32929609