Evidence mapPaperPMID 33188552Full record

Trial reportPhytotherapy research : PTR2021

Bergamot phytosome improved visceral fat and plasma lipid profiles in overweight and obese class I subject with mild hypercholesterolemia: A randomized placebo controlled trial.

Mariangela Rondanelli, Gabriella Peroni, Antonella Riva, Giovanna Petrangolini, Pietro Allegrini, Teresa Fazia, Luisa Bernardinelli, Maurizio Naso, Milena Anna Faliva, Alice Tartara and 3 more

Open access · hybridAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Phytotherapy research : PTR, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
3.5field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 25 citations in OpenAlex.

  1. Effect of Citrus bergamia Supplementation on Body Composition in Humans: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2026
    Pooled it
  2. Pooled it
  3. Trial
  4. Trial
  5. Review
  6. Article
  7. Bergamot (Foods (Basel, Switzerland) · 2024
    Review
  8. Review
  9. Review
  10. Article
  11. Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 2 countries.

Mariangela RondanelliIRCCS Mondino Foundation, Pavia, Italy.
Gabriella PeroniEndocrinology and Nutrition Unit, Azienda di Servizi alla Persona "Istituto Santa Margherita", University of Pavia, Pavia, Italy.ORCID https://orcid.org/0000-0002-1632-1787
Antonella RivaResearch and Development Department, Indena SpA, Milan, Italy.ORCID https://orcid.org/0000-0003-2819-943X
Giovanna PetrangoliniResearch and Development Department, Indena SpA, Milan, Italy.
Pietro AllegriniResearch and Development Department, Indena SpA, Milan, Italy.
Teresa FaziaDepartment of Brain and Behavioral Science, University of Pavia, Pavia, Italy.
Luisa BernardinelliDepartment of Brain and Behavioral Science, University of Pavia, Pavia, Italy.
Maurizio NasoEndocrinology and Nutrition Unit, Azienda di Servizi alla Persona "Istituto Santa Margherita", University of Pavia, Pavia, Italy.
Milena Anna FalivaEndocrinology and Nutrition Unit, Azienda di Servizi alla Persona "Istituto Santa Margherita", University of Pavia, Pavia, Italy.
Alice TartaraEndocrinology and Nutrition Unit, Azienda di Servizi alla Persona "Istituto Santa Margherita", University of Pavia, Pavia, Italy.
Clara GasparriEndocrinology and Nutrition Unit, Azienda di Servizi alla Persona "Istituto Santa Margherita", University of Pavia, Pavia, Italy.
Vittoria InfantinoDepartment of Public Health, Experimental and Forensic Medicine, University of Pavia, Pavia, Italy.ORCID https://orcid.org/0000-0001-8172-5182
Simone PernaDepartment of Biology, University of Bahrain, College of Science, Sakhir, Bahrain.
University of Pavia · ITIndena (Italy) · ITUniversity of Bahrain · BH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bergamot has been traditionally used for the relief of diseases related to oxidative stress. Our aim was to investigate the effect of bergamot phytosome on visceral adipose tissue (VAT) and on metabolic profile, in overweight and obese subjects with mild hypercholesterolemia. A total of 64 participants were randomized into two groups for 12 weeks: a supplemented group (33 individuals, BMI 27 ± 3 kg/m

Indexed as

AdolescentAdultDouble-Blind MethodFemaleHumansHypercholesterolemiaIntra-Abdominal FatLipid MetabolismMaleMiddle AgedObesityOverweightPlant OilsYoung Adultbergamot oilPlant Oilsbergamot phytosomecardiovascular healthdietary supplementhypercholesterolemiaobesityvisceral adipose tissue

Identifiers

PMID33188552
PMCPMC8246838
OpenAlexW3098810672

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.