Evidence map›Paper›PMID 33920623›Full record

Trial reportNutrients2021

Nutritional Controlled Preparation and Administration of Different Tomato Purées Indicate Increase of β-Carotene and Lycopene Isoforms, and of Antioxidant Potential in Human Blood Bioavailability: A Pilot Study.

Daniela Vitucci, Angela Amoresano, Marcella Nunziato, Simona Muoio, Andreina Alfieri, Giovannangelo Oriani, Luca Scalfi, Luigi Frusciante, Maria Manuela Rigano, Piero Pucci and 3 more

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.7field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Tomato (Nutrients · 2026
    Review
  3. Review
  4. Article
  5. Review
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 2 countries.

Daniela VitucciCEINGE-Biotecnologie Avanzate, Via G. Salvatore, 486, 80145 Naples, Italy.
Angela AmoresanoDepartment of Chemical Sciences, University of Naples "Federico II", via Cinthia, 80126 Naples, Italy.
Marcella NunziatoCEINGE-Biotecnologie Avanzate, Via G. Salvatore, 486, 80145 Naples, Italy.ORCID 0000-0003-1999-4992
Simona MuoioDepartment of Public Health, School of Medicine, University of Naples "Federico II", 80131 Naples, Italy.
Andreina AlfieriCEINGE-Biotecnologie Avanzate, Via G. Salvatore, 486, 80145 Naples, Italy.ORCID 0000-0003-1082-1585
Giovannangelo OrianiCEINGE-Biotecnologie Avanzate, Via G. Salvatore, 486, 80145 Naples, Italy.
Luca ScalfiInstitute of Internal Medicine and Metabolic Diseases, Medical School, University of Naples, Federico II, 80131 Naples, Italy.
Luigi FruscianteDepartment of Agricultural Sciences, University of Naples 'Federico II', Via Università 100, Portici, 80055 Naples, Italy.
Maria Manuela RiganoDepartment of Agricultural Sciences, University of Naples 'Federico II', Via Università 100, Portici, 80055 Naples, Italy.ORCID 0000-0001-7826-9067
Piero PucciCEINGE-Biotecnologie Avanzate, Via G. Salvatore, 486, 80145 Naples, Italy.
Luigi FontanaCharles Perkins Center, Faculty of Medicine and Health, University of Sydney, Science Rd, Camperdown, Sydney, NSW 2050, Australia.
Pasqualina BuonoCEINGE-Biotecnologie Avanzate, Via G. Salvatore, 486, 80145 Naples, Italy.
Francesco SalvatoreCEINGE-Biotecnologie Avanzate, Via G. Salvatore, 486, 80145 Naples, Italy.ORCID 0000-0002-2346-3564
Ceinge Biotecnologie Avanzate (Italy) · ITUniversity of Naples Federico II · ITParthenope University of Naples · ITThe University of Sydney · AU

Funding

Regione Campania PON03PE_00060_2
6 · The paper itself

Abstract

The isoforms of lycopene, carotenoids, and their derivatives including precursors of vitamin A are compounds relevant for preventing chronic degenerative diseases such as cardiovascular diseases and cancer. Tomatoes are a major source of these compounds. However, cooking and successive metabolic processes determine the bioavailability of tomatoes in human nutrition. To evaluate the effect of acute/chronic cooking procedures on the bioavailability of lycopene and carotene isoforms in human plasma, we measured the blood levels of these compounds and of the serum antioxidant potential in volunteers after a meal containing two different types of tomato sauce (

Indexed as

AdultAntioxidantsbeta CaroteneBiological AvailabilityCookingCross-Over StudiesFemaleFood HandlingHealthy VolunteersHumansLycopeneMaleMiddle AgedPilot ProjectsProtein IsoformsSolanum lycopersicumAntioxidantsbeta CaroteneLycopeneProtein Isoformsantioxidant powerhuman healthlycopenetomato puréetomato sauces

Identifiers

PMID33920623
PMCPMC8073136
OpenAlexW3155210708

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.