← Statins × all-cause mortality

SynthesisBMC medicine2021

Association of statin use in older people primary prevention group with risk of cardiovascular events and mortality: a systematic review and meta-analysis of observational studies.

Kamal Awad et al.PubMed ↗Full text ↗Publisher ↗

What moved togetherboth groups pooled, not the treatment’s effect

Correlation, not cause

Went with fewer deaths

−14%−21% to −7%

Bigger than 4 in 10 for all-cause mortality

As reported

HR 0.86, 95% CI 0.79–0.93 · the paper's word: All-cause mortality

Correlation, not cause

Went with fewer deaths

−20%−22% to −19%

Bigger than 6 in 10 for all-cause mortality

As reported

HR 0.80, 95% CI 0.78–0.81 · the paper's word: All-cause mortality

Correlation, not cause

Went with fewer deaths

−15%−24% to −6%

Bigger than 5 in 10 for all-cause mortality

As reported

HR 0.85, 95% CI 0.76–0.94 · the paper's word: All-cause mortality

+4 more in the walkthrough ↓

Seven numbers in the abstract

the abstract, start to end

… lower risk of all-cause mortality (HR: 0.86 [95% CI 0.79 to 0.93]), CVD death (HR: 0.80 [95% CI 0.78 to 0.81]), and stroke (HR: 0.85 [95% CI 0.76 to 0.94]) and a non-significant association with risk of MI (HR 0.74 [95% CI 0.53 to 1.02]).

… even at higher ages (> 75 years old; HR 0.88 [95% CI 0.81 to 0.96]) and in both men (HR: 0.75 [95% CI: 0.74 to 0.76]) and women (HR 0.85 [95% CI 0.72 to 0.99]).

← favours treatmentfavours comparator →
could be chance
All-cause mortality
HR 0.860.79–0.93
All-cause mortality
HR 0.800.78–0.81
All-cause mortality
HR 0.850.76–0.94
All-cause mortality
HR 0.740.53–1.02
All-cause mortality
HR 0.880.81–0.96
All-cause mortality
HR 0.750.74–0.76
All-cause mortality
HR 0.850.72–0.99
StatinsAll-cause mortality
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Full record →Abstract, authors, funding and every citing paper · PMID 34154589