Metformin × all-cause mortality

SynthesisDiabetes research and clinical practice2021

The effect of metformin on mortality and severity in COVID-19 patients with diabetes mellitus.

Wenxing Yang et al.PubMed ↗Full text ↗Publisher ↗

What moved togetherboth groups pooled, not the treatment’s effect

Correlation, not cause

Went with fewer deaths

−36%−49% to −21%

Bigger than 8 in 10 for all-cause mortality

As reported

OR 0.64, 95% CI 0.51–0.79 · the paper's word: All-cause mortality

Correlation, not cause

Went with fewer deaths

−19%−34% to −1%

Bigger than 6 in 10 for all-cause mortality

As reported

OR 0.81, 95% CI 0.66–0.99 · the paper's word: All-cause mortality

Two numbers in the abstract

the abstract, start to end

in COVID-19 patients with diabetes (OR = 0.64, 95% CI = 0.51-0.79 for mortality, and OR = 0.81, 95% CI = 0.66-0.99 for

← favours treatmentfavours comparator →
could be chance
All-cause mortality
OR 0.640.51–0.79
All-cause mortality
OR 0.810.66–0.99
MetforminAll-cause mortality
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this paperpooled itcites it
Full record →Abstract, authors, funding and every citing paper · PMID 34302912