Other glucose-lowering × hypoglycaemia

SynthesisFrontiers in endocrinology2022

Relationship Between SGLT-2i and Ocular Diseases in Patients With Type 2 Diabetes Mellitus: A Meta-Analysis of Randomized Controlled Trials.

Bin Zhou et al.PubMed ↗Full text ↗Publisher ↗

What the trial testedas reported · 2022

No range given

Reported lower adverse events & safety, no range given

−53%

Bigger than 8 in 10 for adverse events & safety

As reported

RR 0.47, no interval

No range given

Reported lower adverse events & safety, no range given

−56%

Bigger than 8 in 10 for adverse events & safety

As reported

RR 0.44, no interval

No range given

Reported lower hypoglycaemia, no range given

−50%

Bigger than 8 in 10 on the map

As reported

RR 0.50, no interval

No range given

Reported lower hypoglycaemia, no range given

−53%

Bigger than 8 in 10 on the map

As reported

RR 0.47, no interval

Four numbers in the abstract

the abstract, start to end

Ertugliflozin (RR=0.47, P=0.01) reduced the risk for retinal disease, while empagliflozin (RR=0.44, P=0.05) reduced the risk for

SGLT-2i (RR=0.50, P=0.02), perhaps empagliflozin (RR=0.47, P=0.06), reduced the risk of

← favours treatmentfavours comparator →
could be chance
No interval given · direction only, strength unknown
Adverse events & safety
RR 0.47
Adverse events & safety
RR 0.44
Hypoglycaemia
RR 0.50
Hypoglycaemia
RR 0.47
SGLT2 inhibitorsOther glucose-loweringAdverse events & safetyHypoglycaemia

SGLT2 inhibitors × adverse events & safetyharms?mixed

unlikelylikely
0.00not counted

SGLT2 inhibitors × hypoglycaemiaharms?mixed

unlikelylikely
0.00not counted
← favours treatmentfavours comparator →
more certainless certain
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17 papers cite it

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Full record →Abstract, authors, funding and every citing paper · PMID 35692406