Evidence map›Paper›PMID 36153442›Full record

Trial reportEuropean journal of nutrition2023

Olive pomace oil can improve blood lipid profile: a randomized, blind, crossover, controlled clinical trial in healthy and at-risk volunteers.

Susana González-Rámila, Beatriz Sarriá, Miguel A Seguido, Joaquín García-Cordero, Raquel Mateos, Laura Bravo

Registry-linked trialOpen access · hybridAbstract readRandomized Controlled Trial
In one paragraph

Trial report in European journal of nutrition, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04997122 (Assessment of the Health Effects of Olive Pomace Oil in Healthy and at Risk Consumers), which is not on this map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04997122 nacompletednot on this map

Assessment of the Health Effects of Olive Pomace Oil in Healthy and at Risk Consumers

TypeinterventionalSponsorInstituto de Ciencia y Tecnología de Alimentos y NutriciónRan2018 to 2018Enrolled64ConditionsHealthy, HypercholesterolemiaArmsOlive pomace oil, High oleic acid sunflower oil
3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. DietaryAnimal nutrition (Zhongguo xu mu shou yi xue hui) · 2026
    Article
  4. Review
  5. Synergistic Beneficial Effects of Flaxseed (Food science & nutrition · 2025
    Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Review
  12. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 2 countries.

Susana González-RámilaInstitute of Food Science, Technology and Nutrition (ICTAN-CSIC), Spanish National Research Council (CSIC), José Antonio Nováis 10, 28040, Madrid, Spain.
Beatriz SarriáInstitute of Food Science, Technology and Nutrition (ICTAN-CSIC), Spanish National Research Council (CSIC), José Antonio Nováis 10, 28040, Madrid, Spain.ORCID http://orcid.org/0000-0003-0614-4606
Miguel A SeguidoInstitute of Food Science, Technology and Nutrition (ICTAN-CSIC), Spanish National Research Council (CSIC), José Antonio Nováis 10, 28040, Madrid, Spain.ORCID http://orcid.org/0000-0003-3883-7503
Joaquín García-CorderoInstitute of Food Science, Technology and Nutrition (ICTAN-CSIC), Spanish National Research Council (CSIC), José Antonio Nováis 10, 28040, Madrid, Spain.
Raquel MateosInstitute of Food Science, Technology and Nutrition (ICTAN-CSIC), Spanish National Research Council (CSIC), José Antonio Nováis 10, 28040, Madrid, Spain.ORCID http://orcid.org/0000-0002-9722-1939
Laura BravoInstitute of Food Science, Technology and Nutrition (ICTAN-CSIC), Spanish National Research Council (CSIC), José Antonio Nováis 10, 28040, Madrid, Spain. lbravo@ictan.csic.es.ORCID http://orcid.org/0000-0002-7312-8641
Consejo Superior de Investigaciones Científicas · ES

Funding

Comunidad de Madrid PEJD-2017-PRE/BIO-4225Comunidad de Madrid PEJD-2018-PRE/SAL-9104
6 · The paper itself

Abstract

purposeThis study aimed to assess the effect of dietary consumption of olive pomace oil (OPO) on blood lipids (primary outcome) and other cardiovascular disease (CVD) risk factors (blood pressure, inflammation and endothelial function as secondary outcomes).

methodsA randomized, controlled, blind, crossover intervention was carried out in healthy and at-risk (hypercholesterolemic) subjects. Participants consumed daily 45 g of OPO or high-oleic acid sunflower oil (HOSO) as control oil during 4 weeks.

resultsOPO significantly reduced low-density lipoprotein cholesterol (LDL-C; P = 0.003) and apolipoprotein B (Apo B; P = 0.022) serum concentrations, and LDL/HDL ratio (P = 0.027) in healthy and at-risk volunteers. These effects were not observed with HOSO. Blood pressure, peripheral artery tonometry (PAT), endothelial function and inflammation biomarkers were not affected.

conclusionsRegular consumption of OPO in the diet could have hypolipidemic actions in subjects at cardiovascular risk as well as in healthy consumers, contributing to CVD prevention. CLINICAL TRIAL REGISTRY: NCT04997122, August 8, 2021, retrospectively registered.

Indexed as

Cardiovascular DiseasesCholesterolApolipoproteins BCross-Over StudiesHumansInflammationOleic AcidOlive OilPlant OilsSunflower OilApolipoproteins BCholesterolOleic AcidOlive OilPlant OilsSunflower OilCardiovascular healthEndothelial functionLipid profileOleic acid-rich sunflower oilOlive pomace oil

Identifiers

PMID36153442
PMCPMC9941261
OpenAlexW4296953847

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.