Evidence map›Paper›PMID 38526663›Full record

ArticleApplied biochemistry and biotechnology2024

Chromatographic Fingerprinting of Cacao Pod Husk Extracts (Theobroma cacao L.): Exploring Antibacterial, Antioxidant, and Antidiabetic Properties with In Silico Molecular Docking Analysis.

Hany M Abd El-Lateef, Mai M Khalaf, Manal F Abou Taleb, Mohamed Gouda

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In one paragraph

Article in Applied biochemistry and biotechnology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Hany M Abd El-LateefDepartment of Chemistry, College of Science, King Faisal University, Al-Ahsa, 31982, Saudi Arabia. hmahmed@kfu.edu.sa.
Mai M KhalafDepartment of Chemistry, College of Science, King Faisal University, Al-Ahsa, 31982, Saudi Arabia.
Manal F Abou TalebDepartment of Chemistry, College of Science and Humanities, Prince Sattam Bin Abdulaziz University, Al-Kharj, 11942, Saudi Arabia.
Mohamed GoudaDepartment of Chemistry, College of Science, King Faisal University, Al-Ahsa, 31982, Saudi Arabia. mgoudaam@kfu.edu.sa.

Funding

Deanship of Scientific Research, Vice Presidency for Graduate Studies and Scientific Research at King Faisal University, Saudi Arabia GRANT5,409
6 · The paper itself

Abstract

Natural drugs derived from plants are becoming more popular because of their apparent biological efficacy, affordability, and safety. A byproduct of cocoa farms, cocoa pod husk (CPH), is often disregarded yet contains an abundance of phenolic chemicals that have antimicrobial and antioxidant features, which has led to intensive investigation into possible biomedical applications. In order to identify crucial functional groups and phytochemical components, we carefully examined the 80% ethanol and dichloromethane extracts of CPH using gas chromatography-mass spectrometry (GC-MS) and HPLC. The antibacterial and antioxidant properties of such extracts and their impact on cytotoxicity and α-glucosidase were explored. According to our results, the 80% ethanol and dichloromethane extracts contained 19 and 12 phytochemical components, respectively. Interestingly, at 250 µg/mL, all CPH extracts showed strong antibacterial properties that totally prevented the bacterial growth. At 66.6% and 82.7%, respectively, the ethanol and dichloromethane extracts showed impressive antioxidant and DPPH scavenging capabilities where the ethanol extract showed a substantially lower IC50 value of 35.26 µg/mL than the dichloromethane extract, which had an IC

Indexed as

Anti-Bacterial AgentsAntioxidantsCacaoHypoglycemic AgentsMolecular Docking SimulationPlant Extractsalpha-GlucosidasesChromatography, High Pressure LiquidGas Chromatography-Mass SpectrometryGlycoside Hydrolase InhibitorsHumansalpha-GlucosidasesAnti-Bacterial AgentsAntioxidantsGlycoside Hydrolase InhibitorsHypoglycemic AgentsPlant ExtractsAntibacterial activityAntioxidant activityCPH extractsCytotoxicityPhytochemical constituentsα-Glucosidase inhibition

Identifiers

PMID38526663

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.