Metformin × kidney outcomes

SynthesisThe Cochrane database of systematic reviews2024

Metformin for preventing the progression of chronic kidney disease.

Ragada El-Damanawi et al.PubMed ↗Full text ↗Publisher ↗

  • Metforminno clear effectHigher decline in kidney function.Nothing cleared the noise.

What the trial testedas reported · 505 people · 2024

Not counted

Probably raised decline in kidney function

+1.92mL/min+0.33 to +3.51

metformin vs placebo

As reported

difference 1.92 mL/min, 95% CI 0.33–3.51

Who was studied, and how

505people with type 2 diabetes, in this paper

The trial randomly assignedassigned by chance

metformin
placebo

Probably raised decline in kidney function+1.92

randomised

the abstract, start to end

(3 studies, 505 participants: MD 1.92 mL/min, 95% CI 0.33 to 3.51; I

← favours treatmentfavours comparator →
could be chance
Decline in kidney functionmetformin vs placebo
1.920.33–3.51
MetforminKidney outcomes
1 / 4

13 papers cite it

2024
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Full record →Abstract, authors, funding and every citing paper · PMID 38837240