Metformin × glycemic control

TrialJAMA network open2024

A 5:2 Intermittent Fasting Meal Replacement Diet and Glycemic Control for Adults With Diabetes: The EARLY Randomized Clinical Trial.

Lixin Guo et al.PubMed ↗Full text ↗Publisher ↗

What the trial testedas reported · 509 people · 2024

Not counted

Probably lowered glycemic control

−0.30percentage points−0.40 to −0.10

As reported

difference −0.3 %, 95% CI −0.40 to −0.10

Not counted

Probably lowered glycemic control

−0.40percentage points−0.60 to −0.20

As reported

difference −0.4 %, 95% CI −0.60 to −0.20

Two numbers in the abstract

the abstract, start to end

[SE, 0.2%]; adjusted LSM difference, -0.3% [95% CI, -0.4% to -0.1%]) and empagliflozin

← favours treatmentfavours comparator →
could be chance
Glycemic control
−0.3−0.40 to −0.10
Glycemic control
−0.4−0.60 to −0.20
MetforminSGLT2 inhibitorsGlycemic control
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24 papers cite it

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Full record →Abstract, authors, funding and every citing paper · PMID 38904963