Statins × inflammation & biomarkers

Observational studyInternational urology and nephrology2025

Gut microbiota may mediate the causality of statins on diabetic nephropathy: a mediation Mendelian randomization study.

Xiaoli Wen et al.PubMed ↗Publisher ↗

What moved togetherboth groups pooled, not the treatment’s effect

Correlation, not cause

Went with lower inflammation & biomarkers

−27%−35% to −17%

Bigger than 6 in 10 on the map

As reported

OR 0.732, 95% CI 0.65–0.83

One number in the abstract

the abstract, start to end

incidence of DN (odds ratio [OR]: 0.732, 95% confidence interval [CI]

← favours treatmentfavours comparator →
could be chance
Inflammation & biomarkers
OR 0.7320.65–0.83
StatinsInflammation & biomarkers
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1 paper cites it

2025
this papercites it
Full record →Abstract, authors, funding and every citing paper · PMID 39656409