SynthesisBMJ open2025

Effect of metformin on the clinical outcomes of stroke in patients with diabetes: a systematic review and meta-analysis.

What the trial testedas reported · 525 people · 2025

Not counted

−34%−39% to −28%

Bigger than 8 in 10 for cardiovascular events

As reported

OR 0.66, 95% CI 0.61–0.72

Not counted

−43%−49% to −36%

Bigger than 9 in 10 for cardiovascular events

As reported

OR 0.57, 95% CI 0.51–0.64

the abstract, start to end

… in diabetes mellitus (DM) patients (OR=0.66, 95% CI: 0.61 to 0.72) and reduce the probability of death by 43% (OR=0.57, 95% CI: 0.51 to 0.64).

← favours treatmentfavours comparator →

could be chance

Cardiovascular events

OR 0.660.61–0.72

Cardiovascular events

OR 0.570.51–0.64

MetforminCardiovascular events

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2025

2026

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