GLP-1 receptor agonists × all-cause mortality

SynthesisThe Cochrane database of systematic reviews2025

Glucagon-like peptide 1 (GLP-1) receptor agonists for people with chronic kidney disease and diabetes.

Patrizia Natale et al.PubMed ↗Full text ↗Publisher ↗

What the trial testedrandomised · 48,148 people · 2025

Randomised comparison

Reduced deaths

−15%−26% to −2%

Bigger than 5 in 10 for all-cause mortality

As reported

RR 0.85, 95% CI 0.74–0.98 · the paper's word: All-cause mortality

One number in the abstract

the abstract, start to end

reduced the risk of all-cause death (RR 0.85, 95% CI 0.74 to 0.98; I

← favours treatmentfavours comparator →
could be chance
All-cause mortality
RR 0.850.74–0.98
GLP-1 receptor agonistsAll-cause mortality

GLP-1 receptor agonists × all-cause mortalityhelps?replicated

unlikelylikely
0.88not counted
← favours treatmentfavours comparator →
more certainless certain
1 / 5

9 papers cite it

2025
2026
this paperpooled ittrialcites it
Full record →Abstract, authors, funding and every citing paper · PMID 39963952