Combined liraglutide and metformin therapy in overweight or obese women with polycystic ovary syndrome: A systematic review and meta-analysis.

Liraglutide plus metforminlooks good hereLower fasting blood sugar.Randomised, large.

What the trial testedrandomised · 1,657 people · 2025

Randomised vs metformin alone

−1.92−2.43 to −1.41

liraglutide plus metformin vs metformin alone

As reported

difference −1.92, 95% CI −2.43 to −1.41 · the paper's word: fasting plasma glucose (FPG)

1,657people with type 2 diabetes, in this paper

The trial randomly assignedassigned by chance

liraglutide plus metformin

metformin alone

Lowered fasting blood sugar−1.92

randomised

the abstract, start to end

… FPG (standard mean difference = -1.92, 95% confidence interval [CI] …

← favours treatmentfavours comparator →

could be chance

Fasting plasma glucose (FPG)liraglutide plus metformin vs metformin alone

−1.92−2.43 to −1.41

MetforminGLP-1 receptor agonistsGlycemic control

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2025

2026

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