Evidence map›Paper›PMID 41155358›Full record

ArticleInternational journal of molecular sciences2025

Influence of Coffee Roasting Degree from Four Mexican Regions on In Vitro Antioxidant Activity and Digestive Enzyme Inhibition and Its In Vivo Effects on Carbohydrate and Lipid Absorption.

Claudia I Gamboa-Gómez, Jazel Barragán-Zúñiga, Mayra Denise Herrera, Marilisa Alongi, Nuria E Rocha-Guzmán, Karen M Herrera-Rocha, Deisy Dominguez, Karla F Valles-Araiza, Monica Anese, Martha Rodríguez-Morán and 1 more

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Claudia I Gamboa-GómezUnidad de Investigación Biomédica del Instituto Mexicano del Seguro Social, Canoas 100, Durango 34067, Mexico.ORCID 0000-0002-2815-9406
Jazel Barragán-ZúñigaCentro Estatal de Cancerología, Secretaria de Salud Durango, Av. 5 de Febrero esq. Antonio Norman Fuentes S/N Zona Centro, Durango 34000, Mexico.ORCID 0000-0002-9925-6668
Mayra Denise HerreraInstituto Nacional de Investigaciones Forestales Agrícolas y Pecuarias, Campo Experimental Zacatecas Kilómetro 24.5, Fresnillo 98500, Mexico.
Marilisa AlongiDepartment of Agricultural, Food, Environmental and Animal Sciences, University of Udine, Via Sondrio 2/A, 33100 Udine, Italy.ORCID 0000-0003-4708-6297
Nuria E Rocha-GuzmánTecNM/Instituto Tecnológico de Durango/Laboratorio Nacional Conahcyt de Apoyo a la Evaluación de Productos Bioticos (LaNAEPBi), Blvd. Felipe Pescador 1830 Ote, Colonia Nueva Vizcaya, Durango 34080, Mexico.ORCID 0000-0002-5715-8939
Karen M Herrera-RochaTecNM/Instituto Tecnológico de Durango/Laboratorio Nacional Conahcyt de Apoyo a la Evaluación de Productos Bioticos (LaNAEPBi), Blvd. Felipe Pescador 1830 Ote, Colonia Nueva Vizcaya, Durango 34080, Mexico.
Deisy DominguezUnidad de Investigación Biomédica del Instituto Mexicano del Seguro Social, Canoas 100, Durango 34067, Mexico.
Karla F Valles-AraizaUnidad de Investigación Biomédica del Instituto Mexicano del Seguro Social, Canoas 100, Durango 34067, Mexico.
Monica AneseDepartment of Agricultural, Food, Environmental and Animal Sciences, University of Udine, Via Sondrio 2/A, 33100 Udine, Italy.
Martha Rodríguez-MoránUnidad de Investigación Biomédica del Instituto Mexicano del Seguro Social, Canoas 100, Durango 34067, Mexico.
Fernando Guerrero-RomeroUnidad de Investigación Biomédica del Instituto Mexicano del Seguro Social, Canoas 100, Durango 34067, Mexico.ORCID 0000-0001-9636-9870

Funding

Sistema Nacional de Investigadoras e Investigadores SNI, No. 209339
6 · The paper itself

Abstract

Coffee is among the most consumed beverages worldwide and is recognized for its bioactive compounds, which exert diverse physiological effects. This study evaluated the impact of roasting degree on the in vitro antioxidant activity and digestive enzyme inhibition of brews from four Mexican regions, as well as their in vivo effects on carbohydrate and lipid absorption. Antioxidant capacity was assessed through radical scavenging and lipid peroxidation inhibition, while inhibition of lipase, α-amylase, and α-glucosidase was also determined. Oral starch (OSTT) and lipid (OLTT) tolerance tests were conducted in healthy Wistar rats. Antioxidant activity was strongly influenced by region and roasting degree. All coffee samples exhibited radical scavenging activity and lipid peroxidation inhibition. With respect to enzyme inhibition, all coffees showed ~67-70% inhibition of lipase activity. For amylase, unroasted coffee from Oaxaca displayed the highest inhibition (34%,

Indexed as

AntioxidantsCarbohydrate MetabolismCoffeeCookingEnzyme InhibitorsLipid Metabolismalpha-Amylasesalpha-GlucosidasesAnimalsHot TemperatureLipaseLipid PeroxidationMaleMexicoRatsRats, Wistaralpha-Amylasesalpha-GlucosidasesAntioxidantsCoffeeEnzyme InhibitorsLipasein vitro and in vivo activityMexican coffeephytochemical profileroasting grade

Identifiers

PMID41155358
PMCPMC12564270

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.