GLP-1 receptor agonists × body weight & composition

Observational studyDiabetes, obesity & metabolism2026

Real-world evaluation of clinical outcomes in Dutch patients with type 2 diabetes treated with oral semaglutide: A retrospective, observational cohort study using the PHARMO data network.

Abigail Postema et al.PubMed ↗Full text ↗Publisher ↗

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change in HbA1c from baseline was -16.05 (-12.57, -19.54) mmol/mol at

Body weight was reduced by -4.73 (-3.63, -5.83) kg at 12 months

← favours treatmentfavours comparator →
could be chance
Change in HbA1c from baselineoral semaglutide vs baseline
−16.05−19.5 to −12.6
Body weightoral semaglutide vs baseline
−4.73−5.83 to −3.63
GLP-1 receptor agonistsGlycemic controlBody weight & composition
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