Who Wins the Battle Against Obesity? A Network Meta-Analysis Comparing Tirzepatide and Semaglutide.

What the trial testedrandomised · 367 people · 2026

Randomised comparison

+6.10percentage points+3.64 to +8.57

As reported

difference 6.10 %, 95% CI 3.64–8.57

the abstract, start to end

… weight reduction (mean difference [MD] 6.10%; 95% CI: 3.64, 8.57), absolute …

← favours treatmentfavours comparator →

could be chance

Body weight & composition

6.103.64–8.57

GLP-1 receptor agonistsGIP/GLP-1 & amylin agonistsBody weight & composition

GIP/GLP-1 & amylin agonists × body weight & compositionhelps?replicated

unlikelylikely

1.00not counted

GLP-1 receptor agonists × body weight & compositionhelps?replicated

unlikelylikely

0.90not counted

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more certainless certain

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