ArticleJournal of the science of food and agriculture2026
Valorization of Agave potatorum byproducts as a source of volatile α-glucosidase inhibitors.
Article in Journal of the science of food and agriculture, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
backgroundAgave (Agave potatorum) leaves are an overlooked byproduct of mezcal production. They possess a wealth of secondary metabolites with potential antidiabetic activity. The present study investigated this by identifying volatile constituents associated with in vitro inhibition of α-glucosidase derived from bio-guided hexane fractions of A. potatorum Zucc. leaves. The process involved extraction followed by silica-gel column chromatography, along with bioautography and ultraviolet-visible (UV-visible) assays, using acarbose as the positive control. The two most promising bio-guided fractions were characterized using Attenuated Total Reflection Fourier-Transform Infrared (ATR-FTIR) spectroscopy, phytochemical screening, and gas chromatography-mass spectrometry (GC-MS). Their in silico properties were evaluated through absorption, distribution, metabolism, and excretion (ADME) analysis and molecular docking.
resultsTwo fractions exhibited higher α-glucosidase inhibitory activity with inhibitory concentration (IC
conclusionThis research supports the revalorization of agave byproducts as a viable source of secondary metabolites capable of influencing glucose absorption by α-glucosidase, which is a therapeutic target for addressing type 2 diabetes mellitus, the second leading cause of death worldwide. © 2026 Society of Chemical Industry.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.