GuidelineCirculation2014
2013 ACC/AHA guideline on the treatment of blood cholesterol to reduce atherosclerotic cardiovascular risk in adults: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines.
Erratum issued 16 registry-linked trialsAbstract readPractice Guideline
In one paragraph
Guideline in Circulation, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It reports registered trial NCT02269046. Cited by 1,498 papers, 7 of them syntheses that pooled it.
0numbers the graph read from it
0cells of the map it votes in
1,498citing papers in PubMed, 7 pooled it
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Multi-center, Randomized, Stratified, Active-controlled Trial to Evaluate the Effects of Acupuncture and Moxibustion for Hyperlipidemias
Open the trial in the graphRelationship Between Insulin Resistance and Statin Induced Type 2 Diabetes, and Integrative Personal Omics Profiling
PMID 22883507PMID 23219296PMID 25262344PMID 18551118PMID 25754552PMID 27614854PMID 24326527PMID 25634843PMID 3056758PMID 23706632PMID 22424236PMID 10491414other papers from this trial
Open the trial in the graphA Randomized, Double-Blind, Parallel Group Study to Evaluate the Efficacy and Safety of Bempedoic Acid 180 Mg + Ezetimibe 10 Mg Fixed-Dose Combination Compared to Bempedoic Acid, Ezetimibe, and Placebo Alone in Patients Treated With Maximally Tolerated Statin Therapy
Open the trial in the graphEffect of Virgin Coconut Oil (VCO) on Cardiometabolic Parameters in Patients With Dyslipidemia: A Randomized, add-on, Placebo-controlled Clinical Trial
PMID 15249516PMID 2642759PMID 5787998PMID 4700825PMID 15329324PMID 15364185PMID 17190864PMID 29387131PMID 29079969PMID 28816548PMID 26545671PMID 17635891other papers from this trial
Open the trial in the graphTrial of PCSK9 Inhibition in Patients with Acute Stroke and Symptomatic Intracranial Atherosclerosis - a Prospective, Randomized, Open-label, Blinded End-point Study with High-resolution MR Vessel Wall Imaging
PMID 30403574PMID 25824512PMID 16899775PMID 26671513PMID 16507227PMID 21402390PMID 21427797PMID 21899409PMID 22367991PMID 22568537PMID 23803136PMID 24135208other papers from this trial
Open the trial in the graphPatient and Provider Assessment of Lipid Management Registry
A Placebo-controlled, Double-blind, Randomized Trial to Compare the Effect of Different Doses of ALN-PCSSC Given as Single or Multiple Subcutaneous Injections in Subjects With High Cardiovascular Risk and Elevated LDL-C
A Randomized, Double-blind, Placebo-controlled, Multicenter Long-term Safety and Tolerability Study of ETC-1002 in Patients With Hyperlipidemia at High Cardiovascular Risk Who Are Not Adequately Controlled by Their Lipid-Modifying Therapy
A Long-term, Randomized, Double-blind, Placebo-controlled, Multicenter Study to Evaluate the Efficacy of Bempedoic Acid (ETC-1002) in Patients With Hyperlipidemia at High Cardiovascular Risk Not Adequately Controlled by Their Lipid-Modifying Therapy
A Multicenter Open-Label Extension (OLE) Study To Assess The Long-Term Safety and Efficacy of Bempedoic Acid (ETC-1002) 180 MG
NCT03188978 phase1 / phase2withdrawnnot on this mapstarted 2018, after this paper: background citation
High-intensity Atorvastatin for Arteriovenous Fistula Failure (HAFF): A Feasibility Pilot Study
A Randomized, Double-Blind, Parallel Group, Multicenter Study to Evaluate the Efficacy and Safety of Bempedoic Acid (ETC-1002) 180mg QD When Added to Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9)-Inhibitor Therapy
Assessing Virologic Success and Metabolic Changes in Patients Switching From a TDF to TAF Containing Antiretroviral Therapy Regimen
Pragmatic Randomized Trial of Polygenic Risk Scoring for Common Diseases in Primary Care
Harnessing Evidence And Real-world Data To Improve Cardiovascular Health and Services (HEARTWISE) - The Personalised - CARdiovascular DIsease Risk Assessment for Chinese (P-CARDIAC) Real World Evidence Study - Population-based Study
The Referral to Hepatology Can be Improved Through an Electronic Medical Record (EMR)-Based Best Practice Alert (BPA) for an Appropriate Referral
Who cites it
1,498 citing papers in PubMed, 7 syntheses or guidelines pooled it.
- The Efficacy and Safety of Plozasiran on Lipid Profile in Dyslipidemic Disorders: A Systematic Review and Meta-Analysis.Cardiovascular drugs and therapy · 2026Pooled it
- A Meta-Analysis of the Incidence of Adverse Reactions of Statins in Various Diseases.Cardiovascular therapeutics · 2025Pooled it
- The association between C-reactive protein and coronary artery calcification: a systematic review and meta-analysis.BMC cardiovascular disorders · 2024Pooled it
- Lipid-Lowering Therapy and Risk of Hemorrhagic Stroke: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.Journal of the American Heart Association · 2024 · on this mapPooled it
- Safety and Efficacy of Proprotein Convertase Subtilisin-Kexin Type 9 Inhibitors After Acute Coronary Syndrome: A Meta-analysis of Randomized Controlled Trials.American journal of cardiovascular drugs : drugs, devices, and other interventions · 2024Pooled it
- Safety and efficacy of bempedoic acid: a systematic review and meta-analysis of randomised controlled trials.Cardiovascular diabetology · 2023Pooled it
- Correlation between osteoprotegerin and coronary artery calcification in diabetic subjects: a systematic review of observational studies.BMC cardiovascular disorders · 2023Pooled it
- Perinatal and long-term implications of diagnosing gestational diabetes mellitus using only fasting and one-hour post-load glucose concentrations: Secondary analysis of the GEMS trial and its five-year follow-up.Acta obstetricia et gynecologica Scandinavica · 2026Trial
- Effectiveness and Safety of Bempedoic Acid in Taiwanese Patients With Hypercholesterolemia: A Pragmatic Phase 4 Study (CLEAR Taiwan Study).Journal of the American Heart Association · 2026Trial
- Preliminary results of pravastatin on non-hemorrhagic vertebral artery dissection: an exploratory randomized and controlled study.BMC neurology · 2025Trial
- Association between intensive blood pressure lowering and stroke-free survival among patients with and without Diabetes.Scientific reports · 2024Trial
- Trial
- Potential Cardiovascular Events Avoided with Bempedoic Acid Plus Ezetimibe Fixed-Dose Combination Compared with Ezetimibe Alone in Patients with Atherosclerotic Cardiovascular Disease Taking Maximally Tolerated Statins.American journal of cardiovascular drugs : drugs, devices, and other interventions · 2023Trial
- Long-term cardiovascular risk with cardiovascular-kidney-metabolic syndrome in U.S adults.American heart journal plus : cardiology research and practice · 2026Article
- Efficacy and Safety of an Early Aggressive Lipid-Lowering Strategy Using Triple Therapy After Mechanical Thrombectomy.CNS drugs · 2026Article
- Gender Differences in Statin Discontinuation and Adherence Among Privately Insured People with HIV in the USA.Journal of general internal medicine · 2026 · on this mapObservational
- Review
- Longitudinal association between visceral adiposity index and arthritis-diabetes comorbidity risk: A cohort study from CHARLS.Medicine · 2026Article
- Physician Education and Peer Comparisons to Reduce Cardiovascular Risk Among People Living with HIV: A Stepped-Wedge Cluster Randomized Trial.AIDS and behavior · 2026Article
- Metformin Partially Attenuates Simvastatin-Induced Myotoxic Responses in C2C12 Myotubes Through Metabolic Adaptation.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026Article
1,438 more citing papers are in PubMed but not listed here.
Corrections and comments
- Commented on by
- Commented on by
- Commented on by
- Erratum issuedCorrection.2015
- Erratum issued
Authors and funding
37 authors.
Neil J Stone
Jennifer G Robinson
Alice H Lichtenstein
C Noel Bairey Merz
Conrad B Blum
Robert H Eckel
Anne C Goldberg
David Gordon
Daniel Levy
Donald M Lloyd-Jones
Patrick McBride
J Sanford Schwartz
Susan T Shero
Sidney C Smith
Karol Watson
Peter W F Wilson
Karen M Eddleman
Nicole M Jarrett
Ken LaBresh
Lev Nevo
Janusz Wnek
Jeffrey L Anderson
Jonathan L Halperin
Nancy M Albert
Biykem Bozkurt
Ralph G Brindis
Lesley H Curtis
David DeMets
Judith S Hochman
Richard J Kovacs
E Magnus Ohman
Susan J Pressler
Frank W Sellke
Win-Kuang Shen
Sidney C Smith
Gordon F Tomaselli
American College of Cardiology/American Heart Association Task Force on Practice Guidelines
Funding
No grant is acknowledged in the PubMed record.
Abstract
PubMed holds no abstract for this paper.
Indexed as
American Heart AssociationAnticholesteremic AgentsAtherosclerosisHumansHypercholesterolemiaPrimary PreventionRisk FactorsSecondary PreventionUnited StatesAnticholesteremic AgentsAHA Scientific Statementsbiomarkers, pharmacologicalcardiovascular diseasecholesteroldiabetes mellitusdrug therapyhydroxymethylglutaryl-CoA reductase inhibitors/statinshypercholesterolemialipidspatient complianceprimary preventionrisk assessmentrisk reduction behaviorsecondary prevention
Identifiers
PMID
24222016What Socratic holds
Textmetadata
Read underepoch 390
Registered trials
NCT02269046ClinicalTrials.gov
NCT02437084ClinicalTrials.gov
NCT03337308ClinicalTrials.gov
NCT03906539ClinicalTrials.gov
NCT05001984ClinicalTrials.gov
NCT02341664ClinicalTrials.gov
and 10 more above
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.