SynthesisJournal of the American College of Cardiology2015
Risk of new-onset diabetes and cardiovascular risk reduction from high-dose statin therapy in pre-diabetics and non-pre-diabetics: an analysis from TNT and IDEAL.
Synthesis in Journal of the American College of Cardiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It reports registered trial NCT02437084. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Relationship Between Insulin Resistance and Statin Induced Type 2 Diabetes, and Integrative Personal Omics Profiling
Who cites it
18 citing papers in PubMed, 41 citations in OpenAlex.
- Statins Are Associated With Increased Insulin Resistance and Secretion.Arteriosclerosis, thrombosis, and vascular biology · 2021 · on this mapTrial
- Cost-Effectiveness of Intensifying Lipid-Lowering Therapy With Statins Based on Individual Absolute Benefit in Coronary Artery Disease Patients.Journal of the American Heart Association · 2017Trial
- Metabolic Markers to Predict Incident Diabetes Mellitus in Statin-Treated Patients (from the Treating to New Targets and the Stroke Prevention by Aggressive Reduction in Cholesterol Levels Trials).The American journal of cardiology · 2016 · on this mapTrial
- Cardiovascular outcomes associated with incident diabetes during statin therapy: a nationwide propensity-matched cohort study.Cardiovascular diabetology · 2025Article
- PCSK9 Inhibition and Risk of Diabetes: Should We Worry?Current atherosclerosis reports · 2022Review
- Modest effect of statins on fasting glucose in a longitudinal electronic health record based cohort.Cardiovascular diabetology · 2022Article
- Statins Aggravate the Risk of Insulin Resistance in Human Muscle.International journal of molecular sciences · 2022Article
- Plasma apolipoprotein concentrations and incident diabetes in subjects with prediabetes.Cardiovascular diabetology · 2022Observational
- Updated Understanding of the Crosstalk Between Glucose/Insulin and Cholesterol Metabolism.Frontiers in cardiovascular medicine · 2022Review
- Predictive network modeling in human induced pluripotent stem cells identifies key driver genes for insulin responsiveness.PLoS computational biology · 2020Article
- Association Between Statin Use and Sex Hormone in the Multi-Ethnic Study of Atherosclerosis Cohort.The Journal of clinical endocrinology and metabolism · 2019Article
- Adverse effects of statin therapy: perception vs. the evidence - focus on glucose homeostasis, cognitive, renal and hepatic function, haemorrhagic stroke and cataract.European heart journal · 2018 · on this mapReview
- Diabetes: Anti-PCSK9 antibodies - beneficial or inducers of diabetes?Nature reviews. Endocrinology · 2017Article
- Atorvastatin Induced Adverse Drug Reactions among South Indian Tamils.Journal of clinical and diagnostic research : JCDR · 2017Article
- Statin Use and the Risk of Type 2 Diabetes Mellitus in Children and Adolescents.Academic pediatrics · 2017Article
- Statin use and risk of developing diabetes: results from the Diabetes Prevention Program.BMJ open diabetes research & care · 2017Article
- Very low LDL-C levels may safely provide additional clinical cardiovascular benefit: the evidence to date.International journal of clinical practice · 2016Review
- 2022 Saudi Guidelines for the Management of Dyslipidemia.Heart views : the official journal of the Gulf Heart AssociationArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
PubMed holds no abstract for this paper.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.