SGLT2 inhibitors × cardiovascular events

TrialJournal of diabetes investigation2022

Renal, cardiovascular and safety outcomes of canagliflozin in patients with type 2 diabetes and nephropathy in East and South-East Asian countries: Results from the Canagliflozin and Renal Events in Diabetes with Established Nephropathy Clinical Evaluation Trial.

Takashi Wada et al.PubMed ↗Full text ↗Publisher ↗

What the trial testedas reported · 4,401 people · 2022

Not counted

Reduced cardiovascular events

−46%−65% to −16%

Bigger than 9 in 10 for cardiovascular events

As reported

HR 0.54, 95% CI 0.35–0.84

One number in the abstract

the abstract, start to end

death) in EA participants (hazard ratio 0.54, 95% confidence interval

← favours treatmentfavours comparator →
could be chance
Cardiovascular events
HR 0.540.35–0.84
SGLT2 inhibitorsCardiovascular events
1 / 3

22 papers cite it

2022
2023
2024
2025
2026
this paperpooled ittrialcites it
Full record →Abstract, authors, funding and every citing paper · PMID 34212533