Statins × cardiovascular events

TrialLancet (London, England)2003

Effect of fluvastatin on cardiac outcomes in renal transplant recipients: a multicentre, randomised, placebo-controlled trial.

Hallvard Holdaas et al.PubMed ↗Publisher ↗

What the trial testedas reported · 2,102 people · 2003

Range includes no effect

No clear effect on cardiovascular events

−17%−36% to +6%

Bigger than 4 in 10 for cardiovascular events

As reported

RR 0.83, 95% CI 0.64–1.06

One number in the abstract

the abstract, start to end

for the primary endpoint (risk ratio 0.83 [95% CI 0.64-1.06], p=0.139)

← favours treatmentfavours comparator →
could be chance
Cardiovascular events
RR 0.830.64–1.06
StatinsCardiovascular events

Statins × cardiovascular eventshelps?replicated

unlikelylikely
0.860.86 without it
← favours treatmentfavours comparator →
this papermore certainless certain
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203 papers cite itlatest 60 shown

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The trial

Full record →Abstract, authors, funding and every citing paper · PMID 12814712