Statins × cardiac & vascular function

TrialJAMA2007

Effect of rosuvastatin on progression of carotid intima-media thickness in low-risk individuals with subclinical atherosclerosis: the METEOR Trial.

John R Crouse et al.PubMed ↗Publisher ↗

What the trial testedas reported · 984 people · 2007

No range given

Reported lower lipids, no range given

−49.0percentage points

As reported

difference −49.0 %, no interval

Range includes no effect

No clear effect on cardiac & vascular function

−0.00−0.00 to +0.00

As reported

difference −0.0014, 95% CI −0.00 to 0.00

Range includes no effect

No clear effect on cardiac & vascular function

+0.00−0.00 to +0.00

As reported

difference 0.0004, 95% CI −0.00 to 0.00

Not counted

Probably lowered cardiac & vascular function

−0.00−0.01 to −0.00

As reported

difference −0.0038, 95% CI −0.01 to −0.00

Four numbers in the abstract

the abstract, start to end

to 78 (27.5) mg/dL, a mean reduction of 49% (P<.001 vs placebo group).

CIMT for the 12 carotid sites was -0.0014 (95% CI, -0.0041 to 0.0014)

CIMT for the rosuvastatin group was -0.0038 (95% CI, -0.0064 to -0.0013)

for the common carotid artery sites was 0.0004 (95% CI, -0.0011 to 0.0019)

← favours treatmentfavours comparator →
could be chance
No interval given · direction only, strength unknown
Lipids
−49.0
Cardiac & vascular function
−0.0014−0.00 to 0.00
Cardiac & vascular function
−0.0038−0.01 to −0.00
Cardiac & vascular function
0.0004−0.00 to 0.00
StatinsLipidsCardiac & vascular function

Statins × cardiac & vascular functionhelps?mixed

unlikelylikely
0.500.50 without it

Statins × lipidshelps?mixed

unlikelylikely
0.500.50 without it
← favours treatmentfavours comparator →
this papermore certainless certain
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Full record →Abstract, authors, funding and every citing paper · PMID 17384434